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Turkey Sandwich

Give those holiday leftovers new life with this simple, satisfying turkey sandwich. Layers of leftover turkey, creamy mayo, crisp lettuce, tomato, cheddar, and a bit of cranberry sauce are tucked between toasted bread for the perfect sweet and savory bite.

  • Flavor: Savory turkey, tangy cranberry, and creamy mayo come together for the ultimate leftover lunch.
  • Prep Note: The easiest way to enjoy Thanksgiving leftovers with no cooking at all. Everything’s prepped and ready to layer.
  • Swaps: No leftover turkey? Use pre-sliced deli turkey and your favorite cheese for a quick shortcut.

What You’ll Need:

  • Bread: My family loves sturdy breads like hearty grain bread, ciabatta, rye, or sourdough. Wrap all the ingredients in crisp romaine lettuce for a lighter option.
  • Turkey: Use sliced deli turkey or leftover sliced turkey breast. Add other deli meats like ham, chicken, or cotto salami for variety, or crispy bacon for some extra flavor.
  • Cheese: Choose your cheese; cheddar will give it an extra bite, while mozzarella and provolone will add a milder flavor to the sandwich.
  • Vegetables: Add crunch with lettuce, tomatoes, or cucumbers. For extra creaminess, try sliced avocado.
  • Condiments: Mix mayo with pesto for a flavorful aioli, add a chipotle aioli for a smoky kick, or use honey mustard for a sweet and tangy twist.
  • Variations: Layer in leftover stuffing or drizzle on some gravy to turn it into a hearty, indulgent meal.

More Turkey Sandwich Ideas

  • Hot Open Face: Top slices of turkey on bread, crumble on some dressing, and smother in gravy, like this hot turkey sandwich.
  • Turkey Reuben Panini: If you have a panini press, pile turkey, Swiss cheese, and sauerkraut on buttered rye bread slices, and cook to a golden, crispy crunch. Grilling in a skillet will work too. Serve this one with Thousand Island dressing on the side.
  • Turkey Salad: Make an easy turkey salad recipe and fill croissants or toasted English muffins!
  • Toast the bread, and pat the lettuce and tomatoes dry before layering to keep the sandwich from getting soggy.
  • Warm leftover turkey slightly for a cozy, melty version.
  • Wrap tightly in parchment paper for lunchboxes or picnics.
  • For meal prep, store ingredients separately for up to 3 days, and assemble just before serving.

Storage and Leftovers

Wrap leftover sandwiches tightly and refrigerate up to 1 day for the best texture. Freezing leftovers is not recommended once assembled, but you can freeze leftover turkey up to 4 months!

Perfect Post Holiday Recipes

Did you enjoy this Turkey Sandwich? Leave us a rating and comment below!

Prep Time 15 minutes

Cook Time 0 minutes

Total Time 15 minutes

  • Lightly toast the bread.

  • Spread mayonnaise on 2 of the slices of toasted bread.

  • Top with cheese, turkey, lettuce, and tomatoes. Season with salt & pepper if desired.

  • Spread remaining slices of bread with cranberry sauce and top sandwich.

  • Cut in half and serve.

Top with lettuce, tomatoes, bacon, pickles, or any of your favorite sandwich toppings! 
Sandwiches will keep for 1 day in the refrigerator. 

Calories: 383 | Carbohydrates: 16g | Protein: 11g | Fat: 31g | Saturated Fat: 9g | Cholesterol: 49mg | Sodium: 659mg | Potassium: 77mg | Fiber: 1g | Sugar: 14g | Vitamin A: 284IU | Vitamin C: 1mg | Calcium: 204mg | Iron: 1mg

Nutrition information provided is an estimate and will vary based on cooking methods and brands of ingredients used.

Course Lunch, Sandwich, Turkey
Cuisine American

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